Installation | Look at the raw data | Fortify data | Estimate parameters | Plot results | Simulation of coverage | Design an experiment
This package is considered a duplicate. The official version of this package is found at:https://skgallagher.r-universe.dev/loewesadditivity
Package: loewesadditivity 0.1.0
Shannon Gallagher
loewesadditivity: Loewe's Additivity
Estimate model parameters to determine whether two compounds have synergy, antagonism, or Loewe's Additivity.
Authors:
loewesadditivity_0.1.0.tar.gz
loewesadditivity_0.1.0.zip(r-4.7-any)loewesadditivity_0.1.0.zip(r-4.6-any)loewesadditivity_0.1.0.zip(r-4.5-any)
loewesadditivity_0.1.0.tgz(r-4.6-any)loewesadditivity_0.1.0.tgz(r-4.5-any)
loewesadditivity_0.1.0.tar.gz(r-4.7-any)loewesadditivity_0.1.0.tar.gz(r-4.6-any)
loewesadditivity_0.1.0.tgz(r-4.6-emscripten)
manual.pdf |manual.html✨
DESCRIPTION
card.svg |card.png
loewesadditivity/json (API)
| # Install 'loewesadditivity' in R: |
| install.packages('loewesadditivity', repos = c('https://cranhaven.r-universe.dev', 'https://cloud.r-project.org')) |
Bug tracker:https://github.com/cranhaven/cranhaven.r-universe.dev/issues
Datasets:
- cyrpa_ripr - CyRPA and RIPR
- rh5_ama1ron2 - RH5 and AMA1RON2
- rh5_rh4 - RH5 and RH4
Last updated from:b58b0c5a14 (on package/loewesadditivity). Checks:7 NOTE, 2 OK. Indexed: no.
| Target | Result | Time | Files | Syslog |
|---|---|---|---|---|
| linux-devel | NOTE | 152 | ||
| source / vignettes | OK | 236 | ||
| linux-release | NOTE | 164 | ||
| macos-release | NOTE | 153 | ||
| macos-oldrel | NOTE | 124 | ||
| windows-devel | NOTE | 107 | ||
| windows-release | NOTE | 178 | ||
| windows-oldrel | NOTE | 99 | ||
| wasm-release | OK | 138 |
Exports:%>%base_GIAcalc_Scalc_S_basedesign_experimentestimate_GIAestimate_paramsfortify_gia_datamake_gridplot_curvesplot_isobologramplot_surfacesimulate_coverage
Dependencies:backportscachemcheckmateclassclassIntclicpp11data.tableDBIdigestdplyre1071farverfastmapFormulaformula.toolsgenericsggplot2gluegridExtragtableisobandKernSmoothlabelinglifecyclelubridatemagrittrmemoisemetRoperator.toolspillarpkgconfigplyrproxypurrrR6RColorBrewerRcpprlangrootSolves2S7scalessfstringistringrtibbletidyrtidyselecttimechangeunitsutf8vctrsviridisviridisLitewithrwk
Readme and manuals
Help Manual
| Help page | Topics |
|---|---|
| Estimate GIA according to the base model | base_GIA |
| Helper function for the bootstrap results | boot_GIA |
| Calculate S generally | calc_S |
| Calculate S from given tau_1 for base model | calc_S_base |
| CyRPA and RIPR | cyrpa_ripr |
| Helper function to generate code to run an experiment | design_experiment |
| Function to design an experimental grid of combinations | design_grid |
| Take in dose A and dose B combinations and estimate GIA | estimate_GIA |
| Estimate the parameters for a given data set and model | estimate_params |
| Put GIA measurements into a dplyr format | fortify_gia_data |
| Helper function to get the ED50 line | get_ed_line |
| Make a grid of points | make_grid |
| Plot the surface and observations | plot_curves |
| Plot the estimated isobologram | plot_isobologram |
| Plot the surface and observations | plot_surface |
| RH5 and AMA1RON2 | rh5_ama1ron2 |
| RH5 and RH4 | rh5_rh4 |
| Simulate a GIA model with an assumed error structure | simulate_coverage |
| Calculate the Sum of Squared Error | SSE_GIA |