{ "_id": "6a1018ddacfb0bcc41c85bf1", "Package": "iCARH", "Version": "2.0.2.1", "Date": "2020-08-23", "Title": "Integrative Conditional Autoregressive Horseshoe Model", "Authors@R": "c(person(\"Takoua\", \"Jendoubi\", role = c(\"aut\", \"cre\"), email = \"t.jendoubi14@imperial.ac.uk\"), person(\"Timothy M.D.\", \"Ebbels\", role = c(\"aut\"), email = \"t.ebbels@imperial.ac.uk\") )", "Description": "Implements the integrative conditional autoregressive\nhorseshoe model discussed in Jendoubi, T., Ebbels, T.M.\nIntegrative analysis of time course metabolic data and\nbiomarker discovery. BMC Bioinformatics 21, 11 (2020)\n. The model consists in three\nlevels: Metabolic pathways level modeling interdependencies\nbetween variables via a conditional auto-regressive (CAR)\ncomponent, integrative analysis level to identify potential\nassociations between heterogeneous omic variables via a\nHorseshoe prior and experimental design level to capture\nexperimental design conditions through a mixed-effects model.\nThe package also provides functions to simulate data from the\nmodel, construct pathway matrices, post process and plot model\nparameters.", "biocViews": "", "VignetteBuilder": "knitr", "License": "GPL (>= 3)", "RoxygenNote": "7.1.1", "Encoding": "UTF-8", "NeedsCompilation": "no", "Packaged": { "Date": "2026-05-14 19:40:39 UTC", "User": "root" }, "Author": "Takoua Jendoubi [aut, cre], Timothy M.D. Ebbels [aut]", "Maintainer": "Takoua Jendoubi ", "Config/pak/sysreqs": "cmake libglpk-dev make libicu-dev libxml2-dev\nzlib1g-dev", "Repository": "https://cranhaven.r-universe.dev", "Date/Publication": 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"committer": "GitHub Action ", "message": "Add iCARH to CRANhaven, because archived on 2026-05-14 14:02:00 +0000\n", "time": 1778767320 }, "_maintainer": { "name": "Takoua Jendoubi", "email": "t.jendoubi14@imperial.ac.uk", "login": "takouajendoubi", "uuid": 15359861 }, "_registered": true, "_dependencies": [ { "package": "rstan", "role": "Depends" }, { "package": "MASS", "role": "Depends" }, { "package": "stats", "role": "Depends" }, { "package": "ggplot2", "role": "Depends" }, { "package": "glue", "role": "Depends" }, { "package": "RCurl", "role": "Imports" }, { "package": "KEGGgraph", "role": "Imports" }, { "package": "igraph", "role": "Imports" }, { "package": "reshape2", "role": "Imports" }, { "package": "mc2d", "role": "Imports" }, { "package": "abind", "role": "Imports" }, { "package": "Matrix", "role": "Imports" }, { "package": "knitr", "role": "Suggests" }, { "package": "rmarkdown", "role": "Suggests" } ], "_owner": "cranhaven", "_selfowned": true, "_usedby": 0, "_updates": [ { 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