{
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  "Title": "Escalation with Overdose Control",
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  "Author": "Marcio A. Diniz <marcio.diniz@cshs.org>",
  "Maintainer": "Marcio A. Diniz <marcio.diniz@cshs.org>",
  "Description": "An implementation of a variety of escalation with overdose\ncontrol designs introduced by Babb, Rogatko and Zacks (1998)\n<doi:10.1002/(SICI)1097-0258(19980530)17:10%3C1103::AID-SIM793%3E3.0.CO;2-9>.\nIt calculates the next dose as a clinical trial proceeds and\nperforms simulations to obtain operating characteristics.",
  "License": "GPL (>= 2)",
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  "BugReports": "https://github.com/dnzmarcio/ewoc/issues",
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    "ewoc_d1extended",
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    "pdlt_d1extended",
    "pdlt_d1ph",
    "response_d1classical",
    "response_d1extended",
    "response_d1ph",
    "standard_dose",
    "stop_rule",
    "stop_rule_d1classical",
    "stop_rule_d1extended",
    "stop_rule_d1ph"
  ],
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    {
      "page": "accuracy_index",
      "title": "Accuracy Index",
      "topics": [
        "accuracy_index"
      ]
    },
    {
      "page": "average_toxicity",
      "title": "Average Toxicity Number",
      "topics": [
        "average_toxicity"
      ]
    },
    {
      "page": "dlt_curve_d1classical",
      "title": "Plot the DLT curve based on the EWOC classical model",
      "topics": [
        "dlt_curve_d1classical"
      ]
    },
    {
      "page": "dlt_curve_d1extended",
      "title": "Plot the DLT curve based on the EWOC extended model",
      "topics": [
        "dlt_curve_d1extended"
      ]
    },
    {
      "page": "dlt_curve_d1ph",
      "title": "Plot the DLT curve based on the EWOC proportional hazards model",
      "topics": [
        "dlt_curve_d1ph"
      ]
    },
    {
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      "title": "Evaluation of the DLT rate",
      "topics": [
        "dlt_rate"
      ]
    },
    {
      "page": "ewoc_d1classical",
      "title": "Escalation With Overdose Control",
      "topics": [
        "ewoc_d1classical"
      ]
    },
    {
      "page": "ewoc_d1extended",
      "title": "Escalation With Overdose Control",
      "topics": [
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      ]
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    {
      "page": "ewoc_d1ph",
      "title": "Escalation With Overdose Control",
      "topics": [
        "ewoc_d1ph"
      ]
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    {
      "page": "ewoc_simulation",
      "title": "EWOC simulation",
      "topics": [
        "ewoc_simulation"
      ]
    },
    {
      "page": "inv_standard_dose",
      "title": "Inverse standardization of the dose",
      "topics": [
        "inv_standard_dose"
      ]
    },
    {
      "page": "logit",
      "title": "Logit",
      "topics": [
        "logit"
      ]
    },
    {
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      "title": "Bias of the MTD estimates",
      "topics": [
        "mtd_bias"
      ]
    },
    {
      "page": "mtd_mse",
      "title": "Mean Square Error of the MTD estimates",
      "topics": [
        "mtd_mse"
      ]
    },
    {
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      ]
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        "opc"
      ]
    },
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      ]
    },
    {
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      "title": "Percent of doses in relation the optimal toxicity interval",
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      ]
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      ]
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      ]
    },
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        "pdlt_d1ph"
      ]
    },
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      "title": "Generating a binary response function based on the EWOC classical model",
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      ]
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      ]
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      ]
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      ]
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      "title": "Generating a stop rule function for EWOC extended model",
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    },
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      "title": "Generating a stop rule function for EWOC proportional hazards model",
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