{
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  "Package": "comorbidPGS",
  "Title": "Assessing Predisposition Between Phenotypes using Polygenic\nScores",
  "Version": "1.0.0",
  "Authors@R": "person(\"Vincent\", \"Pascat\", , \"vincent.pascat@univ-lille.fr\", role = c(\"aut\", \"cre\"),\ncomment = c(ORCID = \"0000-0002-6227-8812\"))",
  "Description": "Using polygenic scores (PGS, or PRS/GRS for binary\noutcomes), this package allows to investigate shared\npredisposition between different conditions, and do fast\nassociation analysis, export plots and views of the PGS\ndistribution using 'ggplot2' object.",
  "License": "GPL (>= 3)",
  "Encoding": "UTF-8",
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    "Date": "2026-09-23 20:38:50 UTC",
    "User": "root"
  },
  "Author": "Vincent Pascat [aut, cre] (ORCID:\n<https://orcid.org/0000-0002-6227-8812>)",
  "Maintainer": "Vincent Pascat <vincent.pascat@univ-lille.fr>",
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  "Repository": "https://cranhaven.r-universe.dev",
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  "_updates": [
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  "_tags": [],
  "_topics": [
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    "packages",
    "r-universe"
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  "_stars": 5,
  "_contributors": [
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      "user": "henrikbengtsson",
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    "source": "https://cranlogs.r-pkg.org/downloads/total/last-month/comorbidPGS"
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  "_realowner": "vp-biostat",
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      "date": "2024-04-30"
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    "assocplot",
    "centileplot",
    "decileboxplot",
    "densityplot",
    "mr_2sls",
    "mr_ratio",
    "multiassoc",
    "multiphenassoc"
  ],
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    {
      "name": "comorbidData",
      "title": "Mock dataset for comorbidPGS package",
      "object": "comorbidData",
      "class": [
        "data.table",
        "data.frame"
      ],
      "fields": [
        "ID",
        "sex",
        "age",
        "gen_array",
        "ethnicity",
        "brc_PGS",
        "t2d_PGS",
        "ldl_PGS",
        "brc",
        "t2d",
        "ldl",
        "log_ldl",
        "bmi",
        "sbp",
        "sbp_cat",
        "hypertension"
      ],
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      "table": true,
      "tojson": true
    }
  ],
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    {
      "page": "assoc",
      "title": "Association of a PGS distribution with a Phenotype",
      "topics": [
        "assoc"
      ]
    },
    {
      "page": "assocplot",
      "title": "Multiple PGS Associations Plot",
      "topics": [
        "assocplot"
      ]
    },
    {
      "page": "centileplot",
      "title": "Centiles Plot from a PGS Association",
      "topics": [
        "centileplot"
      ]
    },
    {
      "page": "comorbidData",
      "title": "Mock dataset for comorbidPGS package",
      "topics": [
        "comorbidData"
      ]
    },
    {
      "page": "decileboxplot",
      "title": "Deciles BoxPlot from a PGS Association with a Continuous Phenotype",
      "topics": [
        "decileboxplot"
      ]
    },
    {
      "page": "densityplot",
      "title": "Density Plot from a PGS Association",
      "topics": [
        "densityplot"
      ]
    },
    {
      "page": "mr_2sls",
      "title": "Mendelian Randomization Two-Stage Least Square (2SLS) method with external PGS",
      "topics": [
        "mr_2sls"
      ]
    },
    {
      "page": "mr_ratio",
      "title": "Mendelian Randomization ratio method with external PGS",
      "topics": [
        "mr_ratio"
      ]
    },
    {
      "page": "multiassoc",
      "title": "Multiple PGS Associations from a Data Frame",
      "topics": [
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      ]
    },
    {
      "page": "multiphenassoc",
      "title": "Multiple PGS Associations from different Phenotypes",
      "topics": [
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      ]
    }
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