{
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  "Package": "EBPRS",
  "Type": "Package",
  "Title": "Derive Polygenic Risk Score Based on Emprical Bayes Theory",
  "Version": "2.1.0",
  "Author": "Shuang Song [aut, cre], Wei Jiang [aut], Lin Hou [aut] and\nHongyu Zhao [aut]",
  "Maintainer": "Shuang Song <song-s19@mails.tsinghua.edu.cn>",
  "Description": "EB-PRS is a novel method that leverages information for\neffect sizes across all the markers to improve the prediction\naccuracy.  No parameter tuning is needed in the method, and no\nexternal information is needed. This R-package provides the\ncalculation of polygenic risk scores from the given training\nsummary statistics and testing data. We can use EB-PRS to\nextract main information, estimate Empirical Bayes parameters,\nderive polygenic risk scores for each individual in testing\ndata, and evaluate the PRS according to AUC and predictive r2.\nSee Song et al. (2020) <doi:10.1371/journal.pcbi.1007565> for a\ndetailed presentation of the method.",
  "License": "GPL-3",
  "Encoding": "UTF-8",
  "LazyData": "true",
  "RoxygenNote": "6.1.1",
  "NeedsCompilation": "no",
  "Packaged": {
    "Date": "2026-05-14 19:37:17 UTC",
    "User": "root"
  },
  "Repository": "https://cranhaven.r-universe.dev",
  "Date/Publication": "2026-05-14 12:02:00 UTC",
  "RemoteUrl": "https://github.com/cranhaven/cranhaven.r-universe.dev",
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  "_status": "success",
  "_host": "GitHub-Actions",
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  "_commit": {
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    "author": "GitHub Action <action@github.com>",
    "committer": "GitHub Action <action@github.com>",
    "message": "Add EBPRS to CRANhaven, because archived on 2026-05-14 12:02:00 +0000\n",
    "time": 1778760120
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  "_maintainer": {
    "name": "Shuang Song",
    "email": "song-s19@mails.tsinghua.edu.cn",
    "login": "shuangsong0110",
    "uuid": 56358009
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      "version": ">= 3.5.0",
      "role": "Depends"
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      "role": "Depends"
    },
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      "role": "Depends"
    },
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      "role": "Depends"
    },
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      "role": "Depends"
    }
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  "_selfowned": true,
  "_usedby": 0,
  "_updates": [
    {
      "week": "2026-20",
      "n": 1
    }
  ],
  "_tags": [],
  "_topics": [
    "archived",
    "packages",
    "r-universe"
  ],
  "_stars": 5,
  "_contributors": [
    {
      "user": "henrikbengtsson",
      "count": 183,
      "uuid": 1616850
    }
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  "_userbio": {
    "uuid": 161993010,
    "type": "organization",
    "name": "cranhaven",
    "description": "CRANhaven - Repository for Recently Archived CRAN Packages"
  },
  "_downloads": {
    "count": 207,
    "source": "https://cranlogs.r-pkg.org/downloads/total/last-month/EBPRS"
  },
  "_devurl": "https://github.com/cranhaven/cranhaven.r-universe.dev",
  "_searchresults": 10,
  "_rbuild": "4.6.0",
  "_assets": [
    "extra/citation.cff",
    "extra/citation.html",
    "extra/citation.json",
    "extra/citation.txt",
    "extra/contents.json",
    "extra/EBPRS.html",
    "manual.pdf"
  ],
  "_realowner": "shuangsong0110",
  "_cranurl": false,
  "_releases": [
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      "version": "1.0.1",
      "date": "2018-11-03"
    },
    {
      "version": "1.1.2",
      "date": "2019-02-14"
    },
    {
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      "date": "2019-08-07"
    },
    {
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      "date": "2019-10-10"
    },
    {
      "version": "1.2.1",
      "date": "2019-10-12"
    },
    {
      "version": "1.2.2",
      "date": "2019-11-07"
    },
    {
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      "date": "2020-01-16"
    },
    {
      "version": "2.0.3",
      "date": "2020-02-12"
    },
    {
      "version": "2.0.4",
      "date": "2020-07-10"
    },
    {
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      "date": "2020-08-26"
    }
  ],
  "_exports": [
    "EBPRS",
    "EBPRSpackage",
    "read_plink",
    "validate"
  ],
  "_datasets": [
    {
      "name": "traindat",
      "title": "Example data for training set",
      "object": "traindat",
      "class": [
        "data.table",
        "data.frame"
      ],
      "fields": [
        "CHROM",
        "POS",
        "A1",
        "A2",
        "OR",
        "P",
        "SNP",
        "N"
      ],
      "rows": 100,
      "table": true,
      "tojson": true
    }
  ],
  "_help": [
    {
      "page": "EBPRS",
      "title": "Main function",
      "topics": [
        "EBPRS"
      ]
    },
    {
      "page": "EBPRSpackage",
      "title": "Description of the package",
      "topics": [
        "EBPRSpackage"
      ]
    },
    {
      "page": "read_plink",
      "title": "Read plink bfiles to R and reformat",
      "topics": [
        "read_plink"
      ]
    },
    {
      "page": "traindat",
      "title": "Example data for training set",
      "topics": [
        "traindat"
      ]
    },
    {
      "page": "validate",
      "title": "Validate the performance of EBPRS",
      "topics": [
        "validate"
      ]
    }
  ],
  "_rundeps": [
    "BEDMatrix",
    "bitops",
    "caTools",
    "crochet",
    "data.table",
    "gplots",
    "gtools",
    "KernSmooth",
    "ROCR"
  ],
  "_score": 1.6989700043360187,
  "_indexed": false,
  "_nocasepkg": "ebprs",
  "_universes": [
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  ],
  "_indexurl": "https://shuangsong0110.r-universe.dev/EBPRS",
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