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# CITATION file created with {cffr} R package
# See also: https://docs.ropensci.org/cffr/
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cff-version: 1.2.0
message: 'To cite package "LncPath" in publications use:'
type: software
license: GPL-2.0-or-later
title: 'LncPath: Identifying the Pathways Regulated by LncRNA Sets of Interest'
version: '1.1'
doi: 10.32614/CRAN.package.LncPath
abstract: Identifies pathways synergisticly regulated by the interested lncRNA(long
  non-coding RNA) sets based on a lncRNA-mRNA(messenger RNA) interaction network.
  1) The lncRNA-mRNA interaction network was built from the protein-protein interactions
  and the lncRNA-mRNA co-expression relationships in 28 RNA-Seq data sets. 2) The
  interested lncRNAs can be mapped into networks as seed nodes and a random walk strategy
  will be performed to evaluate the rate of each coding genes influenced by the seed
  lncRNAs. 3) Pathways regulated by the lncRNA set will be evaluated by a weighted
  Kolmogorov-Smirnov statistic as an ES Score. 4) The p value and false discovery
  rate value will also be calculated through a permutation analysis. 5) The running
  score of each pathway can be plotted and the heat map of each pathway can also be
  plotted if an expression profile is provided. 6) The rank and scores of the gene
  list of each pathway can be printed.
authors:
- family-names: Han
  given-names: Junwei
  email: hanjunwei1981@163.com
- family-names: Sun
  given-names: Zeguo
repository: https://cranhaven.r-universe.dev
commit: 9628be81fbec2feec766980b8071bb075c85d9e3
date-released: '2018-09-26'
contact:
- family-names: Han
  given-names: Junwei
  email: hanjunwei1981@163.com